The status-quo and risk factors of liver fluke infection Clonorchis sinensis in humans in Yen Loc commune, Kim Son district, Ninh Binh province

Dr. Pham Thi Ha Trang¹, Assoc. Prof., Dr. Nguyen Thi Thinh², Dr. Truong Van Hanh³ – ¹Ha Noi Department of Health, ²Hoa Binh University, ³National Institute of Malariology Parasitology and Entomology

Abstract:

Clonorchiasis infection is a food-borne parasitic disease that significantly impacts on public health. Among the three species of small liver flukes, Clonorchis sinensis (C. sinensis) is the most prevalent. It is estimated that approximately 35 million individuals worldwide are infected with C. Sinensis, with those affected having a risk of developing cholangiocarcinoma.

Methods: This study employed an analytical descriptive study, conducting cross-sectional surveys involving 459 individuals aged 18 and older at the study site.

Results: The prevalence of infected C. sinensis among humans in Yen Loc commune, Kim Son district, Ninh Binh province, was found to be 19.39%. Of the infected individuals, 92% exhibited mild infectious intensity, with a mean C. sinensis infection intensity of 241.92 ± 481.45 EPG. More male residents (28.44%) were infected with C. sinensis than female (11.20%) residents (p<0.05). Individuals using fresh manure for farming and animal husbandry had 2.04 times higher odds of infection than those who did not utilize fresh manure (95% CI: 1.21-3.43). Furthermore, those consuming raw fish were 7.17 times more likely to be infected compared to those who had never eaten raw fish (95% CI: 3.60-14.27). The highest prevalence of C. sinensis infection was observed in the group people who consumed raw fish once a week (p <0.05).

Conclusion: The prevalence of C. sinensis infection among humans in Yen Loc commune, Kim Son district, Ninh Binh province, is 19.39%, with the majority of cases classified as mild infection intensity.

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Keywords: Clonorchis sinensis; raw fish consumption.